For a safe and effective treatment of stroke

Acticor Biotech is a biopharmaceutical company, founded in 2013 as a spin-off of Inserm (Paris, France), developing an innovative drug for the treatment in the acute phase of ischemic stroke.

According to the World Health Organization, 15 million people suffer stroke worldwide each year. Of these, 6 million die and another 5 million are permanently disabled.

Stroke is the third cause of death in the world and the first cause of adult acquired disabilities resulting

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Acticor Biotech raises €15.3M in a Series B financing

Paris, October 16, 2018 – Acticor Biotech, a clinical stage biotechnology company involved in the acute phase of thrombotic diseases, including stroke and pulmonary embolism, today announced that it has completed a €15.3 million Series B round of financing from European and Asian investors. This new funding will enable the company to finance its first […]
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Strong market potential

Unmeet market needs

15 Million strokes in the world

Annually, 15 million first-ever strokes occur in the world. This number is due to increase because of aging population: in 1990 the world population over 60 years old was 488 millions, in 2030 the projected number is 1,363 millions.

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3rd Cause of Death

Stroke is the 3rd cause of death in industrialized countries (6 million deaths worldwide). The second cause of dementia after Alzheimer's disease and the leading cause of acquired disability in adults. In France, the annual incidence of stroke is estimated at 140,000 cases.

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Major Economic Impact

In addition to being a major public health issue, stroke has a tremendous economic impact. For instance, in 2010 stroke-related medical costs and disability cost about 34 billion dollars to the USA. In the EU countries, the total annual cost of stroke is estimated at 38 billion euros, including the value of informal care.

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Our aim: a drug candidate
with unique benefits

  • Unmeet medical needs in acute stroke

    Despite some health and economic needs, no pharmaceutical treatment is currently satisfactory for the treatment of stroke. Thus, fewer than 10% of patients can be treated with thrombolysis, only effective in the first 4.5h (as approved in EU, 3h in USA) of a stroke, and no existing antiplatelet drugs are suitable for the treatment of acute stroke because of their bleeding risk.

  • A first-in class antithrombotic agent

    Our drug candidate is an antithrombotic agent, designed to reduce the size of the clot, prevent recurrences without bleeding risk and is intended to be used within the first 12 hours.

  • No bleeding risk

    The drug is directed against a novel target of major interest, platelet glycoprotein VI (GPVI) and inhibits its action. Evidence of antithrombotic efficacy and safety of inhibition of GPVI has been established ex vivo but also in in vivo models. The target is involved in the growth of the thrombus and not in physiological hemostasis making the drug candidate the first antithrombotic without bleeding risk.

News & Media

ACT017 : un fragment d’anticorps dont l’ACTion antithrombotique est prometteuse !

Article paru dans Tribune’k Hemostase D’après la communication orale de M. Jandrot-Perrus et al., abstract OC 06.1, 27th Congress of ISTH – International Society on Thrombosis and Haemostasis 2019. Dr Caroline VAYNE, CHRU de Tours Extrait La glycoprotéine GPVI est principalement impliquée dans l’activation plaquettaire en conditions pathologiques et représente donc une cible potentielle pour le […]
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ISTH Honors Five Members with Esteemed Career Awards

“The ISTH honored five individuals with the Esteemed Career Award at the ISTH 2019 Congress Opening Ceremony. These awards are presented annually to individuals whose career contributions have significantly advanced the scientific community’s understanding of diseases and disorders that affect hemostasis. Their accomplishments are internationally regarded as exemplary models of research and mentoring excellence. Congratulations […]
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